Lastminute.com president Ed Kamm is to leave the online retailer after less than a year in the post.
Travelocity Global has announced Kamm will be succeeded by Matthew Crummack, formerly senior vice president of Expedia.
Kamm was appointed in November 2010 after it was announced that Ian McCaig was leaving after five years at lastminute.com.
"After 17 years with Sabre, Travelocity and lastminute.com I have decided that I'm ready to continue my career outside the group but leave confident in the knowledge that the business is in good shape and poised to do well in future with the appointment of Matthew Crummack," Kamm said.
Carl Sparks, president and chief executive of Travelocity Global, added: "I want to thank Ed for his highly-valued leadership and for the continuing progress we have seen at lastminute.com.
“I am delighted that we have an excellent successor in Matthew Crummack. I am very confident that his deep experience in e-commerce, consumer brands, marketing, retail, and online travel make him the perfect leader for the next phase of lastminute.com group's growth."
Crummack said: "lastminute.com is one of the most recognized brands in Europe, with a proud history of innovation, outstanding talent and enviable positions in many of its product lines and services. It's a great honour to join its leadership team and have the opportunity to build on its success."
Crummack oversaw the move of Expedia’s lodging business from the US to Geneva in Switzerland and managed the integration of Venere into Expedia following its acquisition.
Prior to Expedia Matthew was global business development director for Nestle UK, and started his career in sales and marketing in the UK and Europe with Procter & Gamble.